Our research is supported by the CNRS, Aix-Marseille Univ. and by many other funding agencies.

 

Students

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• Emma thesis work is supported by a financial support from the French Ministry of Higher Education and Research.

• Janis thesis work is supported by a financial support from the French Ministry of Higher Education and Research.

• Thomas thesis work is supported by a financial support from the French Ministry of Higher Education and Research.

• Clémentine thesis work is funded by the ANR Sonata project.

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Research Projects from 2004

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• 2024/2027 - ANR Project - Tracer: Mycobacterial envelope contribution in antibiotic translocation, accumulation, efficacy and resistance - Global funding 317 k€. Coordinator: P. Santucci.

 

• 2024/2027 - ANR project - Delirious: Dynamics of intrabacterial lipid inclusions degradation In mycobacteria: unveiling a specific lipolytic platform - Global funding of 468 k€. Coordinator: S. Canaan.

 

• 2023/2026 - FEBS Excellence Awards - Antibiotic mode of action and resistance mechanisms - Global funding 100 k€. Coordinator: P. Santucci.

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• 2024/2028 - PRCI - A*Midex foundation (Aix-Marseille University) - DeNovoCatalysts: Bioinspired de novo metallo-radical proteins conceived for pro-drug activation and oxidation of non-activated hydrocarbons.  Global funding of 259 k€ for the LBP team (Partner: S. Canaan)

 

• 2022/2023 - IM2B new entrant bonus grant. Global funding 8.5 k€. Coordinator: P. Santucci.

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• 2022/2023 - CNRS new entrant bonus grant. Global funding 20 k€. Coordinator: P. Santucci.

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• 2022/2023 - ANRS - Contrat d'initiation - Molecular contribution of pH and the aspartate decarboxylase PanD in pyrazinamide mode of action against Mycobacterium tuberculosis (PanDMyc). Global funding 20 k€. Coordinator: P. Santucci.

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• 2022/2023 - VLM consortium - Vectorisation d’oxadiazolones et d’analogues de Cyclophostine et Cyclipostins par des sidérophores : des chevaux de Troie contre les pathogènes liés à la mucoviscidose. Global funding of 17 k€. Coordinator: S. Canaan.

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• 2020/2021 - "Pépinière d’excellence" A*Midex foundation (Aix-Marseille University) - Development of a new therapeutic tool based on the encapsulation of antimicrobial peptides to fight mycobacterial infections. Global funding of 7.12 k€. Coordinator: M. Casanova.

 

• 2019/2024 - ANR project - ILIome: functional aspects and physiopathological impact of intracytoplasmic lipid inclusions in mycobacteria. Global funding of 556.9 k€ including a post-doctoral fellowship (Ivy Mallick). Coordinator: S. Canaan

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• 2019/2024 - ANR project - LipInTB: new selective Inhibitors for deciphering lipid metabolism and virulence in M. tb. Global funding of 558.8 k€ including a PhD fellowship (Romain Avellan). Coordinator: J.-F. Cavalier.

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• 2019/2022 - VLM consortium - Cyclophostin & Cyclipostins analogs: new therapeutic applications to combat inducible resistance to macrolides in Mycobacterium abscessus. Global funding of 189.0 k€ including a PhD fellowship (Morgane Sarrazin). Coordinator: S. Canaan.

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• 2016/2019 - VLM consortium - New promising scaffolds for the treatment of M. abscessus infections in cystic fibrosis. Global funding of 171.5 k€ including a PhD fellowship (Abdeldjalil Madani). Coordinator: S. Canaan.

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• 2014/2015 - Grant for clinical trials - Performance tests based on the response against lipolytic enzymes of Mycobacterium tuberculosis for diagnosis of active tuberculosis in adults. Global funding of 15.0 k€ for the LBP team (Partner: S. Canaan).

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• 2014/2015 - Carnot Lisa Institute -  Mecanism of action of mycolactone, a toxin responsible for Buruli Ulcer, on model membranes. Global funding of 14.0 k€ for the LBP team. Coordinator: S. Canaan.

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• 2013/2015 - Grant from the IDvet company - Use of M. smegmatis and E. coli as heterologous systems to produce recombinant antigens for the sero-diagnosis of paratuberculosis and bovine tuberculosis. Global funding of 117.3 k€ for the LBP team. Coordinator: S. Canaan.

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• 2013/2015 - European EDCTP Grant - Promoting Infant health and nutrition in Sub-Saharan Africa – Evaluation of Innovative tuberculosis diagnostic tests. Global funding of 118 k€ for the LBP team (Partner: S. Canaan).

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• 2010/2011 - VLM consortium - Bacterial phospholipases C as vaccine candidate antigens in wild mice and DF508: the Mycobacterium abscessus model. Global funding of 5 k€ for the LBP team (Partner).

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• 2009/2013 - ANR - Mechanisms of M. tuberculosis survival: Deciphering the molecular mechanism of lipid acquisition required for persistence within granuloma "foamy" macrophages. Global funding of 122 k€ for the LBP team (Partner: S. Canaan).

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• 2009 - MIE-CNRS grant - In vivo and in vitro studies of phospholipases C from emerging pathogenic Mycobacteria. Global funding of 28 k€ for the LBP team. Coordinator: S. Canaan.

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• 2006/2009 - ANR young researcher grant - Lipolysis and bacterial pathogenicity in M. tuberculosis and M. leprae. Global funding of 120 k€ for the LBP team. Coordinator: S. Canaan.

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