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PUBLICATIONS of the TEAM

2024

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  • Di Maio, A.; Olleik, H.; Courvoisier-Dezord, E.; Guillier, S.; Neulat-Ripoll, F.; Haudecoeur, R.; Bolla, J.-M.; Casanova, M.; Cavalier, J.-F.; Canaan, S.; Pique, V.; Charmasson, Y.; Baydoun, E.; Hijazi, A.; Perrier, J.; Maresca, M.; Robin, M., "Design and Synthesis of Novel Amino and Acetamidoaurones with Antimicrobial Activities", Antibiotics (2024) 13: 300. https://doi.org/10.3390/antibiotics13040300.

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  • Casanova, M.; Maresca, M.; Poncin, I.; Point, V.; Olleik, H.; Boidin-Wichlacz, C.; Tasiemski, A.; Mabrouk, K.; Cavalier, J.-F.; Canaan, S., "Promising antibacterial efficacy of arenicin peptides against the emerging opportunistic pathogen Mycobacterium abscessus", J Biomed Sci. (2024) 31: 18. https://doi.org/10.1186/s12929-024-01007-8.

2023

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  • Dargham, T.; Mallick, I.; Kremer, L.; Santucci, P.; Canaan, S., "Intrabacterial lipid inclusion-associated proteins: A core machinery conserved from saprophyte Actinobacteria to the human pathogen Mycobacterium tuberculosis", FEBS Open Bio (2023) 13: 2306-2323. https://doi.org/10.1002/2211-5463.13721.

 

  • Le, T.T.H.; Kellenberger, C.; Boyer, M.; Santucci, P.; Flaugnatti, N.; Cascales, E.; Roussel, A.; Canaan, S.; Journet, L.; Cambillau, C. "Activity and Crystal Structure of the Adherent-Invasive Escherichia coli Tle3/Tli3 T6SS Effector/Immunity Complex Determined Using an AlphaFold2 Predicted Model", Int J Mol Sci. (2023) 24: 1740. https://doi.org/10.3390/ijms24021740.

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  • Day, N.J..; Santucci, P.; Gutierrez, M.G., "Host cell environments and antibiotic efficacy in tuberculosis", Trends Microbiol. (2023). https://doi.org/10.1016/j.tim.2023.08.009.

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  • Pellegrino, E.; Aylan, B.; Bussi, C.; Fearns, A.; Bernard, EM.; Athanasiadi, N.; Santucci, P.; Botella, L.; Gutierrez, M.G., "Peroxisomal ROS control cytosolic Mycobacterium tuberculosis replication in human macrophages", J Cell Biol (2023) 222(12): e202303066. https://doi.org/10.1083/jcb.202303066.

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  • Kandolo, O.; Cherrak Y.; Filella-Merce, I.; Le Guenno, H.; Kosta, A.; Espinosa, L.; Santucci, P.; Verthuy, C.; Lebrun, R.; Nilges, M.; Pellarin, R.; Durand, E. "Acinetobacter type VI secretion system comprises a non-canonical membrane complex", PLOS Pathog (2023) 19(9): e1011687. https://doi.org/10.1371/journal.ppat.1011687.

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  • Casanova, M.; Olleik, H.; Hdiouech, S.; Roblin, C.; Cavalier, J.-F.; Point, V.; Jeannot, K.; Caron, B.; Perrier, J.; Charriau, S.; Lafond, M.; Guillaneuf, Y.; Canaan, S.; Lefay, C.; Maresca, M., "Evaluation of the Efficiency of Random and Diblock Methacrylate-Based Amphiphilic Cationic Polymers against Major Bacterial Pathogens Associated with Cystic Fibrosis", Antibiotics (2023) 12: 120. https://doi.org/10.3390/antibiotics12010120.

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  • Aylan, B.; Botella, L.; Gutierrez, M.G.; Santucci, P., "High content quantitative imaging of Mycobacterium tuberculosis responses to acidic microenvironments within human macrophages", FEBS Open Bio (2023) 13: 1204-1217. https://doi.org/10.1002/2211-5463.13537.

2022

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  • Bussi, C.; Heunis, T.; Pellegrino, E.; Bernard, E. M.; Bah, N.; Dos Santos, M. S.; Santucci, P.; Aylan, B.; Rodgers, A.; Fearns, A.; Mitschke, J.; Moore, C.; MacRae, J. I.; Greco, M.; Reinheckel, T.; Trost, M.; Gutierrez, M. G., "Lysosomal damage drives mitochondrial proteome remodelling and reprograms macrophage immunometabolism", Nat Commun (2022) 13: 7338.

 

  • Sarrazin, M.; Martin, B. P.; Avellan, R.; Gnawali, G. R.; Poncin, I.; Le Guenno, H.; Spilling, C. D.; Cavalier, J.-F.; Canaan, S., "Synthesis and Biological Characterization of Fluorescent Cyclipostins and Cyclophostin Analogues: New Insights for the Diagnosis of Mycobacterial-Related Diseases", ACS Infect Dis (2022) 8(12): 2564-2578. https://doi.org/10.1021/acsinfecdis.2c00448

 

  • Avellan, R.; Sarrazin, M.; Spilling, C. D.; Crauste, C.; Canaan, S.; Cavalier, J.-F., "Chapter 11 - Deciphering the physiological role of serine enzymes involved in mycobacterial lipid metabolism using activity-based protein profiling". In Biology of Mycobacterial Lipids, Fatima, Z., Canaan, S. (Eds.); Academic Press (2022) pp 235-251. https://doi.org/10.1016/B978-0-323-91948-7.00001-4

 

  • Dargham, T.; Mallick, I.; Raze, D.; Kremer, L.; Canaan, S., "Chapter 12 - Intrabacterial lipid inclusions: overview of an amazing organelle". In Biology of Mycobacterial Lipids, Fatima, Z., Canaan, S. (Eds.); Academic Press (2022) pp 253-269. https://doi.org/10.1016/B978-0-323-91948-7.00003-8

 

  • Le Moigne, V.; Roux, A.L.; Mahoudo, H.; Christien, G.; Ferroni, A.; Dumitrescu, O.; Lina, G.; Bouchara, J.P.; Plésiat, P.; Gaillard, J.L.; Canaan, S.; Héry-Arnaud, G.; Herrmann J.L., "IgA Serological Response for the Diagnosis of Mycobacterium abscessus Infections in Patients with Cystic Fibrosis". Microbiol Spectr. (2022) e0019222. https://doi.org/10.1128/spectrum.00192-22

 

  • Da Prato, L.C.; Zayan, U.; Abdallah, D.; Point, V.; Schaller, F.; Pallesi-Pocachard, E.; Montheil, A.; Canaan, S.; Gaiarsa, J.L.; Muscatelli, F.; Matarazzo, V., "Early life oxytocin treatment improves thermo-sensory reactivity and maternal behavior in neonates lacking the autism-associated gene Magel2". Neuropsychopharmacology (2022), https://doi.org/10.1038/s41386-022-01313-5

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  • Mavrikakia, V.; Pagonisa, A.; Poncin, I.; Mallick, I.; Canaan, S.; Magrioti, V.; Cavalier, J.-F., "Design, synthesis and antibacterial activity against pathogenic mycobacteria of conjugated hydroxamic acids, hydrazides and O-alkyl/O-acyl protected hydroxamic derivatives", Bioorg Med Chem Lett (2022) 64: 128692. https://doi.org/10.1016/j.bmcl.2022.128692

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  • Le Moigne, V.; Roux, A.L.; Mahoudo, H.; Christien, G.; Ferroni, A.; Dumitrescu, O.; Lina, G.; Bouchara, J.P.; Plésiat, P.; Gaillard, J.L.; Canaan, S.; Héry-Arnaud, G.; Herrmann, J.L., "Serological biomarkers for the diagnosis of Mycobacterium abscessus infections in cystic fibrosis patients", J Cyst Fibros. (2022) 21(2): 353-360.

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  • Li, M.; Patel, H. V.; Cognetta, A. B.; Smith, T. C.; Mallick, I.; Cavalier, J.-F.; Previti, M. L.; Canaan, S.; Aldridge, B. B.; Cravatt, B. F.; Seeliger, J. C., "Identification of cell wall synthesis inhibitors active against Mycobacterium tuberculosis by competitive activity-based protein profiling", Cell Chem Biol (2022) 29: 883-896. https://doi.org/10.1016/j.chembiol.2021.09.002

2021

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  • Tasiemski, A.; Wichlacz, C.; Maresca, M.; Canaan, S.; Cavalier, J.-F.; Mabrouk, K.; Hourdez, S., “Antimicrobial peptides, variants and chemical analogues thereof and their uses” EP21306811.7, filled on December 16, 2021.

 

  • Robbe-Saule, M.; Foulon, M.; Poncin, I.; Esnault, L.; Varet, H.; Legendre, R.; Besnard, A.; Grzegorzewicz, A. E.; Jackson, M.; Canaan, S.; Marsollier, L.; Marion, E., "Transcriptional adaptation of Mycobacterium ulcerans in an original mouse model: New insights into the regulation of mycolactone", Virulence (2021) 12: 1438-1451.

 

  • Mallick, I.; Santucci, P.; Poncin, I.; Point, V.; Kremer, L.; Cavalier, J.-F.; Canaan, S., "Intrabacterial lipid inclusions in mycobacteria: unexpected key players in survival and pathogenesis?", FEMS Microbiology Reviews (2021), https://doi.org/10.1093/femsre/fuab029

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  • Cavalier, J.-F.; Spilling, C. D.; Durand, T.; Camoin, L.; Canaan, S., "Lipolytic Enzymes Inhibitors: a new way for Antibacterial Drugs Discovery", Eur J Med Chem (2021) 209: 112908. https://doi.org/10.1016/j.ejmech.2020.112908

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  • Jebli, N.; Arfaoui, Y.; Van Hecke, K.; Cavalier, J.-F.; Touil, S., "Experimental and computational investigation of Z/E isomerism, X-ray crystal structure and molecular docking study of (2-(hydroxyimino)cyclohexyl)diphenylphosphine sulfide, a potential antibacterial agent", J Mol Struct. (2021) 1229: 129634. https://doi.org/10.1016/j.molstruc.2020.129634

2020

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  • Madani, A.; Mallick, I.; Guy, A.; Crauste, C.; Durand, T.; Fourquet, P.; Audebert, S.; Camoin, L.; Canaan, S.; Cavalier, J.-F., "Dissecting the antibacterial activity of oxadiazolone-core derivatives against Mycobacterium abscessus", PLoS ONE (2020) 15(9): e0238178.

 

  • Le Moigne, V.; Roux, A.-L.; Jobart-Malfait, A.; Blanc, L.; Chaoui, K.; Burlet-Schiltz, O.; Gaillard, J.-L.; Canaan, S.; Nigou, J.; Herrmann, J.-L., "A TLR2-Activating Fraction From Mycobacterium abscessus Rough Variant Demonstrates Vaccine and Diagnostic Potential", Front. Cell. Infect. Microbiol. (2020) 10: 432.

 

  • Jebli, N.; Hamimed, S.; Van Hecke, K.; Cavalier, J.-F.; Touil, S., "Synthesis, antimicrobial activity and molecular docking study of novel α-(diphenylphosphoryl)- and α-(diphenylphosphorothioyl)cycloalkanone oximes", Chem. Biodiversity (2020) 17: e2000217.

 

  • Flaugnatti, N.; Rapisarda, C.; Rey, M.; Beauvois, S. G.; Nguyen, V. A.; Canaan, S.; Durand, E.; Chamot-Rooke, J.; Cascales, E.; Fronzes, R.; Journet, L., "Structural basis for loading and inhibition of a bacterial T6SS phospholipase effector by the VgrG spike", EMBO J. (2020) e104129.

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  • Hkiri, S; Hafidh, A; Cavalier, J.-F.; Touil, S.; Samarat, A. "Design, synthesis, antimicrobial evaluation and molecular docking studies of novel symmetrical 2,5-difunctionalized 1,3,4-oxadiazoles", J. Heterocyclic Chem (2020) 57: 1044-1054.

 

  • Yang, D.; Vandenbussche, G.; Vertommen, D.; Evrard, D.; Abskharon, R.; Cavalier, J.-F.; Berger, G.; Canaan, S.; Khan, M. S.; Zeng, S.; Wohlkönig, A.; Prévost, M.; Soumillion, P.; Fontaine, V., "Methyl arachidonyl fluorophosphonate inhibits Mycobacterium tuberculosis thioesterase TesA and globally affects vancomycin susceptibility", FEBS Lett. (2020) 594: 79-93.

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  • Minina, E. A.; Staal, J.; Alvarez, V.E.; Berges, J.A.; Berman-Frank, I.; Beyaert, R.; Bidle, K.D.; Bornancin, F.; Casanova, M. et al. "Classification and nomenclature of metacaspases and paracaspases: no more confusion with caspases” Molecular Cell (2020) 77(5): 927-929.

2019
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  • Basmaciyan, L.; Casanova, M. "Cell death in Leishmania", Parasite (2019) 26, 71.

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  • Marsollier, L.; Aubry, A.; Carbonnelle, E.; Canaan, S.; Laencina, L.; Misguisch, F.; Cambau, E.; Herrmann, J.L. « Mycobactérioses cutanées dues à Mycobacterium ulcerans, Mycobacterium marinum, Mycobacterium abscessus, Mycobacterium chelonae et autres mycobactéries non tuberculeuses », (2019) EMC. [8-038-F-15] DOI: http://dx.doi.org/10.1016/S1166-8598(19)81974-9.

 

  • Bruno, R.; Maresca, M.; Canaan, S.; Cavalier, J.-F.; Mabrouk, K.; Boidin-Wichlacz, C.; Olleik, H.; Zeppilli, D.; Brodin, P.; Massol, F.; Jollivet, D.; Jung, S.; Tasiemski, A., "Worms’ Antimicrobial Peptides", Mar. Drugs (2019) 17: 512.

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  • Madani, A.; Ridenour, J.N.; Martin, B.P.; Paudel, R.R.; Abdul Basir, A.; Le Moigne, V.; Herrmann, J. L.; Audebert, S.; Camoin, L.; Kremer, L.; Spilling, C.D.; Canaan, S.; Cavalier, J.-F., "Cyclipostins and Cyclophostin analogs are multi-target inhibitors that impair growth of Mycobacterium abscessus", ACS Infect Dis. (2019) 5 (9): 1597-1608.

 

  • Santucci, P.; Johansen, M.D.; Point, V.; Poncin, I.; Viljoen, A.; Cavalier, J.-F.; Kremer, L.; Canaan, S. "Nitrogen deprivation induces triacylglycerol accumulation, drug tolerance and hypervirulence in mycobacteria", Scientific Reports (2019) 9(1): 8667.

 

  • Santucci, P.; Smichi, N.; Diomandé, S.; Poncin, I.; Point, V.; Gaussier, H, Cavalier, J.-F.; Kremer, L.; Canaan, S. "Dissecting the membrane lipid binding properties and lipase activity of Mycobacterium tuberculosis LipY domains",  FEBS J. (2019) 286(16): 3164-3181.

 

  • Santucci, P.; Dedaki, C.; Athanasoulis, A.; Gallorini, L.; Munoz, A.; Canaan, S.; Cavalier, J.-F., Magrioti, V. "Synthesis of long chain β-lactones and their antibacterial activities against pathogenic mycobacteria", ChemMedChem (2019) 14(3): 349-358.

 

  • Barreteau, H.; Vandervennet, M.; Guédon, L.; Point, V.; Canaan, S.; Rebuffat, S.; Peduzzi, J.; Carré-Mlouka, A. "Haloarcula sebkhae sp. nov., an extremely halophilic archaeon from Algerian hypersaline environment", Int J Syst Evol Microbiol. (2019) 69: 732-738.

2018
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  • Santucci, P.; Point, V.; Poncin, I.; Guy, A.; Crauste, C.; Serveau-Avesque, C.; Galano, J. M.; Spilling, C. D.; Cavalier, J. F.; Canaan, S. "LipG a bifunctional phospholipase/thioesterase involved in mycobacterial envelope remodeling", Bioscience Reports (2018) 38(6): BSR20181953.

 

  • Nguyen, P. C.; Nguyen, V. S.; Martin, B. P.; Fourquet, P.; Camoin, L.; Spilling, C. D.; Cavalier, J.-F.; Cambillau, C.; Canaan, S. "Biochemical and structural characterization of TesA, a major thioesterase required for outer-envelope lipid biosynthesis in M. tuberculosis", J. Mol. Biol. (2018) 430(24): 5120-5136.

 

  • Nguyen, P. C.; Delorme, V.; Bénarouche A.; Guy, A.; Landry, V.; Audebert, S.; Pophillat, M.; Camoin, L.; Crauste, C.; Galano, J.-M.; Durand, T.; Brodin, P.; Canaan, S.; Cavalier, J.-F. "Oxadiazolone derivatives, new promising multi-target inhibitors against M. tuberculosis", Bioorg Chem. (2018) 81: 414-424.

 

  • Santucci P and Canaan S. "Lipid Droplets Breakdown: Adipose Triglyceride Lipase Leads the Way". Curr Protein Pept Sci. (2018) 19(11): 1131-1133.

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  • Spilling, C. D.; Martin, B. P.; Canaan, S.; Cavalier, J.-F., "Fluorescent Labeled Inhibitors", US10047112B2, filed on August 14, 2018.

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  • Santucci, P.; Diomandé, S.; Poncin, I.; Alibaud, L.; Viljoen, A.; Kremer, L.; de Chastellier, C.; Canaan, S. "Delineating the physiological roles of the PE and catalytic domain of LipY in lipid consumption in mycobacteria-infected foamy macrophages", Infect. Immun. (2018) 86: e00394-18.

 

  • Rénier, W.; Bourdin, A.; Rubbo, P.A.; Peries, M.; Dedieu, L.; Bendriss, S.; Kremer, L.; Canaan, S.; Terru, D.; Godreuil, S.; Nagot, N.; Van de Perre, P.; Tuaillon, E. "B cells response directed against Cut4 and CFP21 lipolytic enzymes in active and latent tuberculosis infections", PLoS ONE (2018) 13(4): e0196470.

 

  • Nguyen, P. C.; Madani, A.; Santucci, P.; Martin, B. P.; Paudel, R. R.; Delattre, S.; Herrmann, J. L.; Spilling, C. D.; Kremer, L.; Canaan, S.; Cavalier, J.-F. "Cyclophostin and Cyclipostins analogs, new promising molecules to treat mycobacterial-related diseases", Int. J. Antimicrob. Agents (2018) 51: 651-654.

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  • Nitenberg, M.; Bénarouche, A.; Maniti, O.; Marion, E.; Marsollier, L.; Géan, J.; Dufourc, E. J.; Cavalier, J.-F.; Canaan, S.; Girard-Egrot, A. P. "The potent effect of mycolactone on lipid membranes" PLoS Pathog (2018) 14(1): e1006814.

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  • Viljoen, A.; Richard, M.; Nguyen, P. C.; Fourquet, P.; Camoin, L.; Paudal, R. R.; Gnawali, G. R.; Spilling, C. D.; Cavalier, J.-F.; Canaan, S.; Blaise, M.; Kremer, L., "Cyclipostins and Cyclophostin analogs inhibit the antigen 85C from Mycobacterium tuberculosis both in vitro and in vivo", J. Biol. Chem.(2018) 293(8): 2755–2769.

2017
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  • Bénarouche, A.; Habchi, J.; Cagna, A.; Maniti, O.; Girard-Egrot, A.; Cavalier, J.-F.; Longhi, S.; Carrière, F., "Interfacial Properties of NTAIL, an Intrinsically Disordered Protein", Biophys J. (2017) 113: 2723-2735.

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  • Nguyen, P. C.; Delorme, V.; Bénarouche, A.; Martin, B. P.; Paudel, R.; Gnawali, G. R.; Madani, A.; Puppo, R.; Landry, V.; Kremer, L.; Brodin, P.; Spilling, C. D.; Cavalier, J.-F.; Canaan, S. "Cyclipostins and Cyclophostin analogs as promising compounds in the fight against tuberculosis", Scientific Reports (2017) 7: 11751.

 

  • Aouani, I.; Sellami, B.; Lahbib, K.; Cavalier, J.-F.; Touil, S. "Efficient synthesis of novel dialkyl-3-cyanopropylphosphate derivatives and evaluation of their anticholinesterase activity", Bioorg. Chem. (2017) 72: 301-307.

 

  • Bouzid F.; Bregeon F; Poncin I.; Weber P.; Drancourt M.; Canaan S. "Mycobacterium canettii infection of adipose tissues", Front. Cell. Infect. Microbiol. (2017) 7: 189.

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  • Spilling, C. D.; Martin, B. P.; Canaan, S.; Cavalier, J.-F. "Fluorescent Labeled Inhibitors", US2017066790, published on March 09, 2017.

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  • Parra J.; Marcoux J.; Poncin I.; Canaan S.; Herrmann J.L.; Nigou J.; Burlet-Schiltz O.; Rivière M. "Scrutiny of Mycobacterium tuberculosis 19 kDa antigen proteoforms provides new insights in the lipoglycoprotein biogenesis paradigm", Scientific Reports (2017) 7: 43682.

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  • Bénarouche A.; Sams L.; Bourlieu C.; Vié V.; Point V.; Cavalier J.-F.; Carrière F. "Studying Gastric Lipase Adsorption Onto Phospholipid Monolayers by Surface Tensiometry, Ellipsometry, and Atomic Force Microscopy", Methods Enzymol (2017) 583: 255-278.

2016
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  • Guerrini V., Subbian S., Santucci P., Canaan S., Gennaro M.L., Pozzi G. "Experimental Evolution of Mycobacterium tuberculosis in Human Macrophages Results in Low-Frequency Mutations Not Associated with Selective Advantage”,  PLoS One (2016) 11: e0167989.

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  • Santucci P.; Bouzid F.; Smichi N.; Poncin I.; Kremer L.; de Chastellier C.; Drancourt M.; Canaan S. "Experimental models of foamy macrophages and approaches for dissecting the mechanisms of lipid accumulation and consumption during dormancy and reactivation of tuberculosis", Front. Cell. Infect. Microbiol. (2016) 6: 122.

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  • Gilleron M.; Lepore M.; Layre E.; Cala-De Paepe D.; Mebarek M.; Shayman JA.; Canaan S.; Mori L.; Carrière F.; Puzo G.; De Libero G. “Lysosomal Lipases PLRP2 and LPLA2 Process Mycobacterial Multi-acylated Lipids and Generate T Cell Stimulatory Antigens”, Cell Chemical Biology (2016) 23: 1147–1156.

 

  • Flaugnatti N.; Le T. T.; Canaan S.; Aschtgen M. S.; Nguyen V. S.; Blangy S.; Kellenberger C.; Roussel A.; Cambillau C.; Cascales E.; Journet L. "A phospholipase A1 antibacterial Type VI secretion effector interacts directly with the C-terminal domain of the VgrG spike protein for delivery", Mol. Microbiol (2016) 99: 1099-1118.

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  • Bourlieu C.; Paboeuf G.; Chever S.; Pezennec S.; Cavalier J.-F.; Guyomarc’h F.; Deglaire A.; Bouhallab S.; Dupont D.; Carrière F.; Vié V., "Adsorption of gastric lipase onto multicomponent model lipid monolayers with phase separation", Colloids Surf B: Biointerfaces (2016) 143: 97-106.

 

  • Lemarié F.; Cavalier J.-F.; Garcia C.; Boissel F.; Point V.; Catheline D.; Legrand P.; Carrière F.; Rioux V. "Effect of preduodenal lipase inhibition in suckling rats on dietary octanoic acid (C8:0) gastric absorption and plasma octanoylated ghrelin concentration", Biochim Biophys Acta (2016) 1861: 1111-1120.

 

  • Point V.; Bénarouche A.; Zarillo J.; Guy A.; Magnez R.; Fonseca L.; Raux B.; Leclaire J.; Buono G.; Fotiadu F.; Durand T.; Carrière F.; Vaysse C.; Couëdelo L.; Cavalier J.-F. "Slowing down fat digestion and absorption by an oxadiazolone inhibitor targeting selectively gastric lipolysis", Eur J Med Chem. (2016) 123: 834-848.

 

  • Ulker S.; Placidi C.; Point V.; Gadenne B.; Serveau-Avesque C.; Canaan S.; Carriere F.; Cavalier J.-F. "New lipase assay using Pomegranate oil coating in microtiter plates", Biochimie (2016) 120: 110-118.

 

  • Aboubaker Osman D.; Bouzid F.; Canaan S.; Drancourt M. "Smooth Tubercle Bacilli: Neglected Opportunistic Tropical Pathogens", Frontiers in Public Health (2016) 3: 283.

2015

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  • Spilling C. D.; Martin B. P.; Canaan S.; Cavalier J.-F. "Fluorescent Labeled Inhibitors", WO2015127381A1, filed on August 27, 2015.

 

  • Le Moigne V.; Rottman M.; Goulard C.; Barteau B.; Poncin I.; Soismier N.; Canaan S.; Pitard B.; Gaillard J. L.; Herrmann J. L. "Bacterial phospholipases C as vaccine candidate antigens against cystic fibrosis respiratory pathogens: the Mycobacterium abscessus model", Vaccine (2015) 33: 2118-2124.

2014

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  • Bakala N' Goma J.-C.; Le Moigne V.; Soismier N.; Laencina L.; Le Chevalier F.; Roux A.-L.; Poncin I.; Serveau–Avesque C.; Rottman M.; Gaillard J.-L.; Etienne G.; Brosch R.; Herrmann J.-L.; Canaan S.; Girard-Misguich F. "Mycobacterium abscessus Phospholipase C expression is induced during co-culture within amoeba and enhances M. abscessus virulence in mice", Infect Immun. (2014) 83: 780-791.

 

  • Amara S.; Patin A.; Giuffrida F.; Wooster T. J.; Thakkar S. K.; Benarouche A.; Poncin I.; Robert S.; Point V.; Molinari S.; Gaussier H.; Diomande S.; Destaillats F.; Cruz-Hernandez C.; Carriere F. "In vitro digestion of citric acid esters of mono- and diglycerides (CITREM) and CITREM-containing infant formula/emulsions", Food & function (2014) 5: 1409-1421.

 

  • Delorme V.; Raux B.; Puppo R.; Leclaire J.; Cavalier J.-F.; Marc S.; Kamarajugadda P.-K.; Buono G.; Fotiadu F.; Canaan S.; Carrière F. "Supported inhibitor for fishing lipases in complex biological media and mass spectrometry identification", Biochimie (2014) 107: 124-134.

 

  • Caire-Brändli I.; Papadopoulos A.; Malaga W.; Marais D.; Canaan S.; Thilo L.; de Chastellier C. "Reversible lipid accumulation and associated division arrest of Mycobacterium avium in lipoprotein-induced foamy macrophages may resemble key events during latency and reactivation of tuberculosis", Infect. Immun. (2014) 82: 476-490.

2013

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  • Point V.; Malla R. K.; Carriere F.; Canaan S.; Spilling C. D.; Cavalier, J.-F., "Enantioselective Inhibition of microbial lipolytic enzymes by non-racemic monocyclic enolphosphonate analogs of Cyclophostin", J Med Chem (2013) 56: 4393-4401.

 

  • Dedieu L.; Serveau-Avesque C.; Kremer L.; Canaan S. "Mycobacterial lipolytic enzymes: A gold mine for tuberculosis research", Biochimie (2013) 95: 66-73

 

  • Dedieu L.; Serveau-Avesque C.; Canaan S. "Identification of residues involved in substrate specificity and cytotoxicity of two closely related cutinases from Mycobacterium tuberculosis", PLoS ONE (2013) 8: e66913.

2012

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  • Shen G.; Singh K.; Chandra D.; Serveau-Avesque C.; Maurin D.; Canaan S.; Singla R.; Behera D.; Laal S. "LipC (Rv0220) is an immunogenic cell surface esterase of Mycobacterium tuberculosis", Infection and Immunity (2012) 80: 243-253.

 

  • Delorme V.; Diomandé S.; Dedieu L.; Cavalier J.-F.; Carrière F.; Kremer L.; Leclaire J.; Fotiadu F.; Canaan S. "MmPPOX Inhibits Mycobacterium tuberculosis Lipolytic Enzymes Belonging to the Hormone-Sensitive Lipase Family and Alters Mycobacterial Growth", PLoS ONE (2012) 7: e46493.

 

  • Point V.; Pavan Kumar K. V. P.; Marc S.; Delorme V.; Parsiegla G.; Amara S.; Carrière F.; Buono G.; Fotiadu F.; Canaan S.; Leclaire J.; Cavalier J.-F. "Analysis of the discriminative inhibition of mammalian digestive lipases by 3-phenyl substituted 1,3,4-oxadiazol-2(3H)-ones", Eur J Med Chem. (2012) 58: 452-463.

 

  • Point V.; Malla R. K.; Diomande S.; Martin B. P.; Delorme V.; Carriere F.; Canaan S.; Rath N. P.; Spilling C. D.; Cavalier J.-F. "Synthesis and kinetic evaluation of Cyclophostin and Cyclipostins phosphonate analogs as selective and potent inhibitors of microbial lipases", J. Med. Chem. (2012) 55: 10204-10219.

2011

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  • Delorme V.; Dhouib R.; Canaan S.; Fotiadu F.; Carrière F.; Cavalier J.-F. "Effects of Surfactants on Lipase Structure, Activity and Inhibition", Pharm. Res (2011) 28: 1831-1842.

 

  • Laurent Marsollier, Alexandra Aubry, Etienne Carbonnelle, Stéphane Canaan, Emmanuelle Cambau, Jean louis Herrmann « Les Mycobactérioses cutanées dues à Mycobacterium ulcerans, Mycobacterium marinum, Mycobacterium abscessus, Mycobacterium chelonae et autres mycobactéries non tuberculeuses », (2011) EMC. [8-038-F-15] Doi: https://doi.org/10.1016/S1166-8598(11)56475-80.

 

  • Brust B.; Lecoufle M.; Tuaillon E.; Dedieu L.; Canaan S.; Valverde V.; Kremer, L. "Mycobacterium tuberculosis Lipolytic Enzymes as Potential Biomarkers for the Diagnosis of Active Tuberculosis", PLoS ONE (2011) 6: e25078.

 

  • Palmieri-Thiers C.; Alberti J.C.; Canaan S.; Brunini V.; Gambotti C.; Tomi F.; Oliw EH.; Berti L.; Maury J. “Identification of putative residues involved in the accessibility of the substrate-binding site of lipoxygenase by site-directed mutagenesis studies”. Arch Biochem Biophys. (2011) 509: 82-89.

 

  • Dhouib R.; Ducret A.; Hubert P.; Carriere F.; Dukan S.; Canaan S. "Watching intracellular lipolysis in mycobacteria using time lapse fluorescence microscopy", Biochim Biophys Acta (2011) 1811: 234-241

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