Oxadiazolone Derivatives: Powerful Tools to Reduce Staphylococcus aureus Infection Forest E., Lehoux J., Faion L., Ranava D., Mohymont V., Durand T., Audebert S., Camoin L., Crauste C., Canaan S., Brunel J. M., Van Bambeke F., Bolla J.-M., Cavalier, J.-F. Staphylococcus aureus is a Gram-positive opportunistic pathogen and a top priority bacterium in the fight against antimicrobial resistance. Its high propensity to develop resistance, its high virulence, and its ability to fo

Mycobacterial cell division arrest and smooth-to-rough envelope transition using CRISPRi-mediated genetic repression systems Point, V., Achache, W., Laudouze, J., Sepulveda Ramos, E., Maziero, M., Crauste, C., Canaan, S. and Santucci, P. The genetic basis underlying nontuberculous mycobacteria (NTM) pathogenesis remains poorly understood. This gap in knowledge has been partially filled over the years through the generation of novel and efficient genetic tools, including the r

Cyclophostin and Cyclipostins analogues counteract macrolide-induced resistance mediated by erm(41) in Mycobacterium abscessus Sarrazin,...